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He used it in 1798 in the long title of his Inquiry into the Variolae vaccinae known as the Cow Pox, in which he described the protective effect of cowpox against smallpox.

In early 2008, there were 64 suspected cases of measles.

Other diseases such as rubella, polio, measles, mumps, chickenpox, and typhoid are nowhere near as common as they were a hundred years ago.

As long as the vast majority of people are vaccinated, it is much more difficult for an outbreak of disease to occur, let alone spread. Polio, which is transmitted only between humans, is targeted by an extensive eradication campaign that has seen endemic polio restricted to only parts of three countries (Afghanistan, Nigeria, and Pakistan).

The classic example is Jenner's use of cowpox to protect against smallpox.

A current example is the use of BCG vaccine made from Mycobacterium bovis to protect against human tuberculosis.

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